Synonyms: Quinine bisulfate, Quinine hydrogen sulfate, dihydrate
CAS No.: 804-63-7
Molecular Weight: 782.96
Chemical Formula: (C20H24N2O2)2H2SO4.2H2O
Product Codes: U768
Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------------ --------- Quinine Sulfate Dihydrate 804-63-7 90 - 100% Yes
Emergency Overview
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WARNING! HARMFUL IF SWALLOWED. MAY BE HARMFUL IF INHALED. AFFECTS CARDIOVASCULAR AND CENTRAL NERVOUS SYSTEM. MAY CAUSE IRRITATION TO SKIN, EYES, AND RESPIRATORY TRACT.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 2 - Moderate
Flammability Rating: 1 - Slight
Reactivity Rating: 0 - None
Contact Rating: 1 - Slight
Lab Protective Equip: GOGGLES; LAB COAT
Storage Color Code: Orange (General Storage)
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Potential Health Effects
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Hazard information based on health hazards of the general class of chemicals consisting of quinidines and quinines.
Inhalation:
May cause irritation to the respiratory tract. Symptoms may include coughing and shortness of breath. Can be route for absorption in the body. See ingestion.
Ingestion:
Affects the cardiovascular and central nervous systems. Produces lethargy, drowsiness, irritability, ringing in the ears, headache, dizziness, nausea, vomiting, diarrhea and hot flushed skin. Allergic responses, including skin rashes and drug fever may occur. Large doses can produce heart and respiratory failure.
Skin Contact:
Mild irritant to skin. May have some absorption. Sensitivity reactions can occur.
Eye Contact:
May cause irritation, redness and pain.
Chronic Exposure:
May produce central nervous system depression which may lead to cardiac and respiratory dysfunction.
Aggravation of Pre-existing Conditions:
Persons with prior nervous system, cardiac or respiratory problems may be more susceptible to this substance. Some individuals are very sensitive to this substance. Sensitization from previous exposures are not uncommon, but rarely life threatening.
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact:
Immediately flush skin with plenty of soap and water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention if irritation develops.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
Fire:
As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source.
Explosion:
Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
Remove all sources of ignition. Ventilate area of leak or spill. Keep unnecessary and unprotected people away from area of spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Pick up and place in a suitable container for reclamation or disposal, using a method that does not generate dust.
Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect from physical damage. Separate from oxidizing materials. Store in the dark. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.
Airborne Exposure Limits:
None established.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to the dust or mist is apparent, a half-face dust/mist respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear protective gloves and clean body-covering clothing.
Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.
Appearance:
White powder.
Odor:
Odorless.
Solubility:
Practically insoluble in water.
Density:
No information found.
pH:
6.2
% Volatiles by volume @ 21C (70F):
0
Boiling Point:
No information found.
Melting Point:
ca. 100C (ca. 212F) Loses water
Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
No information found.
Evaporation Rate (BuAc=1):
No information found.
Stability:
Stable at room temperature in sealed containers. Sensitive to light and loses water with heat.
Hazardous Decomposition Products:
Oxides of carbon, sulfur and nitrogen may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Ammonia, alkalis, strong oxidizers, tannic acid, acetates, citrates, tartrates, benzoates, and salicylates.
Conditions to Avoid:
Heat, incompatibles.
No LD50/LC50 information found relating to normal routes of occupational exposure. Anhydrous: Investigated as a mutagen, reproductive effector.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Quinine Sulfate Dihydrate No No None
(804-63-7)
Environmental Fate:
No information found.
Environmental Toxicity:
No information found.
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
Not regulated.
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Quinine Sulfate Dihydrate (804-63-7) Yes Yes No Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Quinine Sulfate Dihydrate (804-63-7) No Yes No No
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Quinine Sulfate Dihydrate (804-63-7) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
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Quinine Sulfate Dihydrate (804-63-7) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: No Pressure: No
Reactivity: No (Mixture / Solid)
Australian Hazchem Code: None allocated.
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.
NFPA Ratings: Health: 2 Flammability: 1 Reactivity: 0
Label Hazard Warning:
WARNING! HARMFUL IF SWALLOWED. MAY BE HARMFUL IF INHALED. AFFECTS CARDIOVASCULAR AND CENTRAL NERVOUS SYSTEM. MAY CAUSE IRRITATION TO SKIN, EYES, AND RESPIRATORY TRACT.
Label Precautions:
Avoid breathing dust.
Keep container closed.
Avoid contact with eyes, skin and clothing.
Use only with adequate ventilation.
Wash thoroughly after handling.
Label First Aid:
If swallowed, induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes. Get medical attention if irritation develops or persists.
Product Use:
Laboratory Reagent.
Revision Information:
No changes.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
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Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)